Enhanced roll porous scaffold 3D bioprinting technology

Abstract

The upgrade of the Roll Porous Scaffold (RPS) 3D bioproduction technique provides significant advantages over today’s dominant analogues. The density 10–15 µm cells in the formed object increased up to ~1.26×10⁸ cells/mL. The improvement of droplet inkjet methods is achieved by draining excess water through a comb. In addition, a modified foam/lattice-based structure of the scaffold <1% w/v with a new support ribbon ensures cleaner and more precise biological object shaping. The updated RPS offers not only new hope for overcoming the shortage of organs for transplantation but rejuvenation of the whole organism due to the forming of your own endocrine glands. It should be noted that albeit RPS is a project and never used, it is a derivative of the time-tested methods and components of bioprinting. Potential of RPS for building of multicellular tissue of high density and accuracy, equipped with a vascular system, with a width of 333 mm and a volume >1.7 L per hour at a layer thickness of 18 μm.